Expression of respiratory mucins in fatal status asthmaticus and mild asthma.

@article{Groneberg2002ExpressionOR,
  title={Expression of respiratory mucins in fatal status asthmaticus and mild asthma.},
  author={David A. Groneberg and Paul R. Eynott and Sy Lim and T Oates and R Wu and Ingemar Carlstedt and Pamela. Roberts and B. Mccann and Andrew G. Nicholson and B D Harrison and Kian Fan Chung},
  journal={Histopathology},
  year={2002},
  volume={40 4},
  pages={
          367-73
        }
}
  • David A. Groneberg, Paul R. Eynott, +8 authors Kian Fan Chung
  • Published in Histopathology 2002
  • Medicine
  • AIMS The airways of patients with asthma are characterized by chronic inflammatory changes comprising mainly T-cells and eosinophils, and airway remodelling with goblet cell metaplasia and submucosal gland hyperplasia. Mucus hypersecretion is often a marked feature, particularly in status asthmaticus. The matrix of airway sputum consists of high molecular glycoproteins and mucins. In this study, the expression and distribution of the major gel-forming mucins MUC5AC and MUC5B were studied in… CONTINUE READING

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