Expression of renal transport systems for inorganic phosphate and sulfate in Xenopus laevis oocytes.

@article{Werner1990ExpressionOR,
  title={Expression of renal transport systems for inorganic phosphate and sulfate in Xenopus laevis oocytes.},
  author={Andreas Werner and Juerg Biber and Judith Forgo and Manuel Palac{\'i}n and Heini Murer},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 21},
  pages={12331-6}
}
As a first step within an experimental strategy (expression cloning) leading to the structural identification of the two brush-border membrane transport systems for phosphate and sulfate, we have studied the expression of Na(+)-dependent uptake of phosphate and sulfate in Xenopus laevis oocytes injected with rabbit kidney cortex poly(A)+ RNA (mRNA). Na(+)-dependent uptake of phosphate and sulfate was stimulated in a dose- and time-dependent manner up to 20-fold as compared to water-injected… CONTINUE READING

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