Expression of recombinant dystrophin and its localization to the cell membrane.

Abstract

Duchenne's muscular dystrophy (DMD) is an X-linked progressive myopathy caused by a defect in the DMD gene locus. The gene corresponding to the DMD locus produces a 14-kilobase (kb) messenger RNA that codes for a large cytoskeletal membrane protein, dystrophin. DMD and Becker's muscular dystrophy are the consequences of dystrophin mutations. The exact… (More)

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Cite this paper

@article{Lee1991ExpressionOR, title={Expression of recombinant dystrophin and its localization to the cell membrane.}, author={Chin Chin Lee and Joe Pearlman and J S Chamberlain and C. Thomas Caskey}, journal={Nature}, year={1991}, volume={349 6307}, pages={334-6} }