Expression of receptors for human angiogenin in vascular smooth muscle cells.

@article{Hatzi1999ExpressionOR,
  title={Expression of receptors for human angiogenin in vascular smooth muscle cells.},
  author={Elissavet Hatzi and Josette Badet},
  journal={European journal of biochemistry},
  year={1999},
  volume={260 3},
  pages={825-32}
}
Human angiogenin is a plasma protein with angiogenic and ribonucleolytic activities. Angiogenin inhibited both DNA replication and proliferation of aortic smooth muscle cells. Binding of 125I-angiogenin to bovine aortic smooth muscle cells at 4 degrees C was specific, saturable, reversible and involved two families of interactions. High-affinity binding sites with an apparent dissociation constant of 0.2 nm bound 1 x 104 molecules per cell grown at a density of 3 x 104.cm-2. Low-affinity… CONTINUE READING
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