Expression of pulmonary surfactant protein D in rat gastric mucosa.

  title={Expression of pulmonary surfactant protein D in rat gastric mucosa.},
  author={James H. Fisher and Ralph Mason},
  journal={American journal of respiratory cell and molecular biology},
  volume={12 1},
Gastric mucosa is protected from an acidic lumenal environment by an extracellular layer composed in part of phospholipids that are similar in composition to the phospholipids of lung surfactant. The function and metabolic processing of lung surfactant is regulated, in part, by surfactant specific proteins. We speculated that the gastric extracellular acid barrier might be regulated by such proteins. We demonstrate by RNA blot analysis, RT-PCR, and immunostaining and protein blot the synthesis… CONTINUE READING

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