Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina.

@article{Kramerov2006ExpressionOP,
  title={Expression of protein kinase CK2 in astroglial cells of normal and neovascularized retina.},
  author={Andrei A. Kramerov and Mehrnoosh Saghizadeh and Hao Pan and Andrea Kabosova and Mathias Montenarh and Khalil Ahmed and John S. Penn and Candy K. Chan and David R Hinton and Maria B Grant and Alexander V Ljubimov},
  journal={The American journal of pathology},
  year={2006},
  volume={168 5},
  pages={1722-36}
}
We previously documented protein kinase CK2 involvement in retinal neovascularization. Here we describe retinal CK2 expression and combined effects of CK2 inhibitors with the somatostatin analog octreotide in a mouse model of oxygen-induced retinopathy (OIR). CK2 expression in human and rodent retinas with and without retinopathy and in astrocytic and endothelial cultures was examined by immunohistochemistry, Western blotting, and reverse transcriptase-polymerase chain reaction. A combination… CONTINUE READING