Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations.

@article{Gagnerault1993ExpressionOP,
  title={Expression of prolactin receptors in murine lymphoid cells in normal and autoimmune situations.},
  author={M C Gagnerault and Philippe Touraine and Wilson Savino and Paul A. T. Kelly and Mireille Dardenne},
  journal={Journal of immunology},
  year={1993},
  volume={150 12},
  pages={5673-81}
}
We have analyzed the expression of prolactin receptors (PRL-R) on murine lymphoid cells by using flow cytofluorometry analysis with biotinylated anti-PRL-R mAb raised against several epitopes of the extracellular domain of the PRL-R and by using polymerase chain reaction amplification. We demonstrated that PRL-R were universally expressed in normal rat and mouse hematopoietic tissues. In both primary lymphoid organs, namely, thymus and bone marrow, > 90% of cells were labeled by the anti-PRL-R… CONTINUE READING

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