Expression of progesterone receptor A form and its role in the interaction of progesterone with cortisol on cyclooxygenase-2 expression in amnionic fibroblasts.

@article{Guo2009ExpressionOP,
  title={Expression of progesterone receptor A form and its role in the interaction of progesterone with cortisol on cyclooxygenase-2 expression in amnionic fibroblasts.},
  author={C. Guo and X. Zhu and X. Ni and Z. Yang and L. Myatt and K. Sun},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2009},
  volume={94 12},
  pages={
          5085-92
        }
}
  • C. Guo, X. Zhu, +3 authors K. Sun
  • Published 2009
  • Biology, Medicine
  • The Journal of clinical endocrinology and metabolism
  • CONTEXT Human amnion fibroblasts produce abundant prostaglandins toward the end of gestation, which is believed to be one of the major events leading to parturition. Glucocorticoids have been shown to up-regulate cyclooxygenase-2 (COX-2) expression, the crucial enzyme catalyzing prostaglandin synthesis, in human amnion fibroblasts. Although a major propregnancy hormone, the effect of progesterone and the associated progesterone receptor subtypes in the regulation of both basal and… CONTINUE READING
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    References

    SHOWING 1-10 OF 37 REFERENCES
    Paradoxical stimulation of cyclooxygenase-2 expression by glucocorticoids via a cyclic AMP response element in human amnion fibroblasts.
    • 34
    • PDF
    Glucocorticoids stimulate prostaglandin H synthase type-2 (PGHS-2) in the fibroblast cells in human amnion cultures
    • 81
    Progesterone receptor profile in the decidua and fetal membrane.
    • S. Goldman, E. Shalev
    • Chemistry, Medicine
    • Frontiers in bioscience : a journal and virtual library
    • 2007
    • 21
    • PDF
    Glucocorticoids stimulate prostaglandin synthesis in human amnion cells by a receptor-mediated mechanism.
    • 87
    Nuclear progesterone receptors in the human pregnancy myometrium: evidence that parturition involves functional progesterone withdrawal mediated by increased expression of progesterone receptor-A.
    • 189
    • PDF
    Progesterone production by human fetal membranes: an in vitro incubation system for studying hormone production and metabolism.
    • 33
    Glucocorticoids induce cytosolic phospholipase A2 and prostaglandin H synthase type 2 but not microsomal prostaglandin E synthase (PGES) and cytosolic PGES expression in cultured primary human amnion cells.
    • Kang Sun, R. Ma, +4 authors L. Myatt
    • Biology, Medicine
    • The Journal of clinical endocrinology and metabolism
    • 2003
    • 69
    • PDF