Expression of pro-inflammatory and anti-inflammatory cytokines in brain of atherosclerotic rats and effects of Ginkgo biloba extract

@article{Jiao2005ExpressionOP,
  title={Expression of pro-inflammatory and anti-inflammatory cytokines in brain of atherosclerotic rats and effects of Ginkgo biloba extract},
  author={Yachong Jiao and Y. Rui and Tie-jun Li and Peng Yang and Y. Qiu},
  journal={Acta Pharmacologica Sinica},
  year={2005},
  volume={26},
  pages={835-839}
}
AbstractAim:To study the protein and mRNA expressions of pro-inflammatory and antiinflammatory cytokines in the brain of rats with atherosclerosis (AS) and the effects of Ginkgo biloba extract (GbE) on expressions of cytokines.Methods:The experimental model of AS in rats were established by intraperitioneal injection of vitamin D3 with high fat/cholesterol diet. GbE 100 mg/kg was administered to rats by ig. After 8 weeks, the expressions of IL-1β, TNF-α, IL-10, and IL-10R in the brain tissues… Expand
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