Expression of platelet-derived growth factor (PDGF) in the epididymis and analysis of the epididymal development in PDGF-A, PDGF-B, and PDGF receptor beta deficient mice.

@article{Basciani2004ExpressionOP,
  title={Expression of platelet-derived growth factor (PDGF) in the epididymis and analysis of the epididymal development in PDGF-A, PDGF-B, and PDGF receptor beta deficient mice.},
  author={Sabrina Basciani and Stefania Mariani and Mario Arizzi and Marina Brama and Andrea Ricci and Christer Betsholtz and Cecilia Bondjers and Giulia Ricci and Angela Catizone and M. Teresa Galdieri and Giovanni Spera and Lucio Gnessi},
  journal={Biology of reproduction},
  year={2004},
  volume={70 1},
  pages={
          168-77
        }
}
The platelet-derived growth factor (PDGF) family of ligands and receptors play a pivotal role in the development of various organs. The critical importance of the PDGF-mediated signaling during embryonic development and adult physiology of the kidney and the common mesonephric origin of the epididymis and kidney prompted us to investigate the immunohistochemical localization of PDGF A- and B-chain and PDGF receptor (PDGFR) alpha- and beta-subunit in rat and mouse epididymis, the expression… CONTINUE READING

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