Expression of phosphorylated Stat5 predicts expression of cyclin D1 and correlates with poor prognosis of colonic adenocarcinoma

@article{Mao2010ExpressionOP,
  title={Expression of phosphorylated Stat5 predicts expression of cyclin D1 and correlates with poor prognosis of colonic adenocarcinoma},
  author={Yinling Mao and Zhiwei Li and Changjie Lou and Yanqiao Zhang},
  journal={International Journal of Colorectal Disease},
  year={2010},
  volume={26},
  pages={29-35}
}
Constitutive activation of signal transducer and activator of transcription-5 (Stat5) was recently found to be associated with tumor progression through stimulating cell proliferation and preventing apoptosis. However, it is not clear how activated Stat5 is expressed in colon cancer. We aimed to investigate the correlation between phosphorylated Stat5 (p-Stat5) expression and cell cycle regulators (cyclin D1) expression in colonic adenocarcinoma and the relationship between expression of these… CONTINUE READING
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