Expression of p53-related protein p63 in the gastrointestinal tract and in esophageal metaplastic and neoplastic disorders.

@article{Glickman2001ExpressionOP,
  title={Expression of p53-related protein p63 in the gastrointestinal tract and in esophageal metaplastic and neoplastic disorders.},
  author={Jonathan N Glickman and Annie Yang and Aliakbar Shahsafaei and Frank McKeon and Robert D Odze},
  journal={Human pathology},
  year={2001},
  volume={32 11},
  pages={1157-65}
}
p63 is a p53-related DNA-binding protein that helps regulate differentiation and proliferation in epithelial progenitor cells. Its expression has never been evaluated in the human gastrointestinal tract. The aim of this study was to evaluate the expression of p63 in the esophagus and related metaplastic and neoplastic disorders to gain insight into the pathogenesis of these processes. Of particular interest was the expression of p63 in Barrett esophagus (BE) and in BE-associated multilayered… CONTINUE READING

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