Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin.

@article{Saito1999ExpressionOP,
  title={Expression of p53 protein and Ki-67 antigen in gingival hyperplasia induced by nifedipine and phenytoin.},
  author={Kumi Saito and Shunsuke Mori and Nobuya Tanda and Shinichi Sakamoto},
  journal={Journal of periodontology},
  year={1999},
  volume={70 6},
  pages={581-6}
}
BACKGROUND Although it has been thought that drug-induced gingival hyperplasia is not related to tumorigenesis, recent case reports have shown that squamous cell carcinomas may arise in gingival hyperplasia induced by cyclosporin and phenytoin. The possible implications between the pathogenesis of this disease and tumorigenesis have not been elucidated and remain to be studied. METHODS We immunohistochemically examined the expression of tumor-related markers such as p53 protein and Ki-67… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 13 extracted citations

Similar Papers

Loading similar papers…