Expression of p53 oncoprotein in non-small-cell lung cancer: a favorable prognostic factor.

@article{Lee1995ExpressionOP,
  title={Expression of p53 oncoprotein in non-small-cell lung cancer: a favorable prognostic factor.},
  author={J S Lee and Alice Yoon and Shyla K Kalapurakal and Jae Yoon Ro and J Jack Lee and Nora Tu and Walter N. Hittelman and Waun Ki Hong},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1995},
  volume={13 8},
  pages={1893-903}
}
PURPOSE Mutation of the p53 gene is one of the most common genetic abnormalities found in lung cancer. The purpose of this study was to evaluate the prognostic value of p53 oncoprotein expression in patients with non-small-cell lung cancer (NSCLC). PATIENTS AND METHODS We studied 156 resected primary NSCLCs by the immunohistochemical staining technique, using the p53 antibody DO7. There were 81 adenocarcinomas, 16 large-cell carcinomas, and 59 squamous cell carcinomas; stages were I in 67, II… CONTINUE READING
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