Expression of p53, p21/waf1, bcl-2, bax, Rb and Ki67 proteins in Hodgkin's lymphomas.

@article{Kanavaros2000ExpressionOP,
  title={Expression of p53, p21/waf1, bcl-2, bax, Rb and Ki67 proteins in Hodgkin's lymphomas.},
  author={Panayiotis Kanavaros and Kalliope Stefanaki and Jean Vlachonikolis and George D. Eliopoulos and Stylianos Souglakos John Kakolyris and Dimitra Rontogianni and V Gorgoulis and Vassileios Georgoulias},
  journal={Histology and histopathology},
  year={2000},
  volume={15 2},
  pages={
          445-53
        }
}
The aim was to investigate the combined immunoexpression of p53, p21, bcl-2, bax, Rb and Ki67 proteins in Hodgkin's lymphomas (HL) and correlate expression patterns with the histotype and the Epstein-Barr Virus (EBV) status. Paraffin-sections from 56 cases of HL (18 nodular sclerosis and 38 mixed cellularity) and from ten "reactive" lymph nodes were investigated. P53, p21, bcl-2, bax, Rb and Ki67 proteins were detected in Hodgkin and Reed-Sternberg (HRS) cells in 35/56, 56/56, 24/56, 23/56, 56… CONTINUE READING