Expression of p16 in benign and malignant cystic squamous lesions of the neck.

@article{Cao2010ExpressionOP,
  title={Expression of p16 in benign and malignant cystic squamous lesions of the neck.},
  author={Dengfeng Cao and Shahnaz Begum and Syed Zulfiqar Ali and William H Westra},
  journal={Human pathology},
  year={2010},
  volume={41 4},
  pages={535-9}
}
Metastatic cystic squamous cell carcinomas of the neck often harbor human papillomavirus 16 and, in turn, overexpress p16. P16 immunohistochemistry could be useful in the evaluation of patients who present with cystic squamous lesions of the neck, particularly when the distinction between a benign lymphoepithelial cyst and a metastatic squamous cell carcinoma cannot be easily resolved on clinical or pathologic grounds. Implementation of this strategy, however, awaits a description of p16… CONTINUE READING
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