Expression of p16 alone does not differentiate between Spitz nevi and Spitzoid melanoma.


BACKGROUND Spitz nevi and Spitzoid melanomas show overlapping histopathologic features, often making the diagnosis challenging. The p16 protein functions as a tumor suppressor and loss of its expression may be seen in some melanomas. METHODS We evaluated 18 Spitz nevi and 19 Spitzoid melanomas from the Yale Spitzoid Neoplasm Repository for p16 expression… (More)
DOI: 10.1111/cup.12014


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