Expression of p-glycoprotein in multidrug-resistant human leukemia k562 cells during erythroid-differentiation.

Abstract

Expression of P-glycoprotein (P-gp), the multidrug resistance gene product, has previously been shown to be downregulated during differentiation of normal haematopoietic cells. In order to determine whether such a regulation also occurs in leukemic cells, we have investigated the relevance of differentiation levels to P-gp expression in multidrug-resistant… (More)

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@article{Fardel1995ExpressionOP, title={Expression of p-glycoprotein in multidrug-resistant human leukemia k562 cells during erythroid-differentiation.}, author={Olivier Fardel and Fabienne Escande and B. Rault and Bernard Dr{\'e}nou and J Lebescot and Ren{\'e}e Fauchet}, journal={International journal of oncology}, year={1995}, volume={7 2}, pages={377-81} }