Expression of osteoblastic and osteoclastic genes during spontaneous regeneration and autotransplantation of goldfish scale: a new tool to study intramembranous bone regeneration.

@article{Thamamongood2012ExpressionOO,
  title={Expression of osteoblastic and osteoclastic genes during spontaneous regeneration and autotransplantation of goldfish scale: a new tool to study intramembranous bone regeneration.},
  author={Thiparpa Aime Thamamongood and Ryo Furuya and Shunsuke Fukuba and Masahisa Nakamura and Nobuo Suzuki and Atsuhiko Hattori},
  journal={Bone},
  year={2012},
  volume={50 6},
  pages={1240-9}
}
Complementary DNA of osteoblast-specific genes (dlx5, runx2a, runx2b, osterix, RANKL, type I collagen, ALP, and osteocalcin) was cloned from goldfish (Carassius auratus) scale. Messenger RNA expressions were analyzed during spontaneous scale regeneration. Dlx5 had an early peak of expression on day 7, whereas osterix was constantly expressed during days 7-21. Runx2, a major osteoblastic transcription factor in mammalian bone, did not show any significant expression. The expressions of two… CONTINUE READING

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