Expression of opioid receptors during heart ontogeny in normotensive and hypertensive rats.

@article{Zimlichman1996ExpressionOO,
  title={Expression of opioid receptors during heart ontogeny in normotensive and hypertensive rats.},
  author={Reuven Zimlichman and Dov Gefel and Haskel E Eliahou and Ziporah Matas and Bruce Rosen and Sabine Gass and Catherine Ela and Yael Eilam and Zvi Vogel and Jacob Barg},
  journal={Circulation},
  year={1996},
  volume={93 5},
  pages={1020-5}
}
BACKGROUND The opioidergic systems are involved in modulating nociceptive stimuli. In addition, the recent results suggest that endogenous and exogenous opioids could play a role in the modulation of blood pressure and cardiac functions. However, little is known regarding the expression and role of opioid-binding sites in the heart. The decreased sensitivity to noxious stimuli in hypertensive rats raises the possibility of different developmental pattern expression of opioid-binding sites in… CONTINUE READING

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