Expression of olfactory-type cyclic nucleotide-gated channel (CNGA2) in vascular tissues

@article{Cheng2003ExpressionOO,
  title={Expression of olfactory-type cyclic nucleotide-gated channel (CNGA2) in vascular tissues},
  author={Kwong-Tai Cheng and Franky Chan and Yu Huang and W Chan and Xiao-qiang Yao},
  journal={Histochemistry and Cell Biology},
  year={2003},
  volume={120},
  pages={475-481}
}
Cyclic nucleotide-gated (CNG) ion channels are Ca2+-permeable nonselective cation channels that are directly gated by the binding of cAMP or cGMP. Previous studies have identified the expression of CNGA1 channels in vascular endothelial cells. The opening of CNG channels is expected to result in a rise in endothelial cytosolic Ca2+, which may trigger multiple physiological changes. In the present study, we extensively studied the expression pattern of the functional subunit of olfactory-type… CONTINUE READING