Expression of nuclear receptor coregulators in ovarian stromal and epithelial tumours.

@article{HusseinFikret2005ExpressionON,
  title={Expression of nuclear receptor coregulators in ovarian stromal and epithelial tumours.},
  author={Sonay Hussein-Fikret and Peter J. Fuller},
  journal={Molecular and cellular endocrinology},
  year={2005},
  volume={229 1-2},
  pages={149-60}
}
Granulosa cell tumours of the ovary (GCT) exhibit high expression of estrogen receptor beta (ERbeta). A role for estrogen receptors in these tumours may depend on altered co-activator expression. This study examines the expression of the co-activators SRC-1a/e, SRC-2, SRC-3, SRA, and the corepressors NCoR and SMRT in GCT, epithelial ovarian tumours and normal ovary. No significant difference in the expression of SRC-1, SRC-2, SRC-3 or NCoR and SMRT was found. In particular, there was no… CONTINUE READING

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