Expression of nonclassical MHC class I (RT1-U) in certain neuronal populations of the central nervous system.

@article{Lidman1999ExpressionON,
  title={Expression of nonclassical MHC class I (RT1-U) in certain neuronal populations of the central nervous system.},
  author={Olle Lidman and Tomas Olsson and Fredrik Piehl},
  journal={The European journal of neuroscience},
  year={1999},
  volume={11 12},
  pages={4468-72}
}
Major histocompatibility complex (MHC) class I genes consist of classical (Ia) and nonclassical (Ib) types. Recently, a set of structurally similar MHC class Ib genes in the rat, denoted RT1-U, was described. We here demonstrate expression of RT1-U mRNA using highly stringent oligonucleotide in situ hybridization in several different neuronal populations, including different motor nuclei and the substantia nigra in the rat MHC (c) and (n) haplotypes under normal conditions. The expression… CONTINUE READING

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