Expression of nm23 in the primary tumor and the metastatic regional lymph nodes of patients with gastric cardiac cancer.

@article{Hsu1999ExpressionON,
  title={Expression of nm23 in the primary tumor and the metastatic regional lymph nodes of patients with gastric cardiac cancer.},
  author={N Y Hsu and K C Chow and Wen Jun Chen and Curtis Chun-Jen Lin and F F Chou and Chun-ling Chen},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={1999},
  volume={5 7},
  pages={1752-7}
}
Tumor recurrence and distant metastasis are major causes of treatment failure in gastric cardiac cancer (GCC). Rapid growth of tumor cells and reduced expression of nm23, a metastatic suppressor gene, in tumor cells have been suggested as two important mechanisms for disease progression of GCC. Therefore, to determine the prognostic value of nm23 expression in GCC, we used immunohistochemistry to examine the expression of nm23 in the pathological sections of both gastric cancer and metastatic… CONTINUE READING
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