Expression of nitric oxide synthase in the spinal cord in C57BL/6J mice with congenital muscular dystrophy.

@article{Phul2000ExpressionON,
  title={Expression of nitric oxide synthase in the spinal cord in C57BL/6J mice with congenital muscular dystrophy.},
  author={Ravinder Phul and Margaret Elizabeth Smith},
  journal={Muscle & nerve},
  year={2000},
  volume={23 1},
  pages={63-72}
}
Autoradiography with the nitric oxide synthase (NOS) inhibitor ((3)H)nitro-L-arginine ([(3)H]L-NNA) was used to quantify NOS in cervical and lumbar spinal cord in normal and dystrophic mice. A single homogeneous population of binding sites was seen in all subregions of the gray matter in normal mice and in the superficial dorsal horn in dystrophic mice. However, in dystrophic mice, two populations were revealed in the deeper dorsal, intermediate, and ventral subregions. Pronounced… CONTINUE READING