Expression of neurotrophin-3 in the mouse forebrain: insights from a targeted LacZ reporter.

@article{Vigers2000ExpressionON,
  title={Expression of neurotrophin-3 in the mouse forebrain: insights from a targeted LacZ reporter.},
  author={Alison J Vigers and Zachary C. Baquet and Kevin R. Jones},
  journal={The Journal of comparative neurology},
  year={2000},
  volume={416 3},
  pages={
          398-415
        }
}
To obtain insights into the expression of neurotrophin-3 (NT-3) in the mouse, we have utilized mice in which the Escherichia coli lacZ gene is integrated into the neurotrophin-3 locus (NT-3(lacZneo), Fariñas et al. [1994] Nature 369:658-661). In this mouse strain, beta-galactosidase production is under control of the NT-3 promoter in its normal chromosomal environment, and histochemical measurement of beta-galactosidase provides a simple, sensitive method to determine which cells express NT-3… CONTINUE READING
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