Expression of neuronal nuclear antigen (NeuN) in epithelial neuroendocrine carcinoma.

@article{Shuangshoti2005ExpressionON,
  title={Expression of neuronal nuclear antigen (NeuN) in epithelial neuroendocrine carcinoma.},
  author={Shanop Shuangshoti and Sukrutai Mujananon and Mookda Chaipipat and Kanista Keetacheeva and Somruetai Shuangshoti},
  journal={Applied immunohistochemistry & molecular morphology : AIMM},
  year={2005},
  volume={13 3},
  pages={265-7}
}
Expression of neuronal nuclei (NeuN), a mouse-derived neuronal-specific monoclonal antibody, has been found in almost all neuronal cell types throughout the nervous system. The authors have demonstrated NeuN immunoreactivity in 56% of epithelial neuroendocrine carcinomas (ENEC) (19/34): 4 of 7 (57%) grade 1 ENECs (carcinoid), 4 of 5 (90%) grade 2 ENECs (atypical carcinoid), and 11 of 22 (50%) grade 3 ENECs (small and large cell neuroendocrine carcinoma). Of the NeuN-positive cases, the… CONTINUE READING