Expression of neural cell adhesion molecule in normal and neoplastic human neuroendocrine tissues.

@article{Jin1991ExpressionON,
  title={Expression of neural cell adhesion molecule in normal and neoplastic human neuroendocrine tissues.},
  author={Long Jin and John J. Hemperly and Ricardo Vincent Lloyd},
  journal={The American journal of pathology},
  year={1991},
  volume={138 4},
  pages={961-9}
}
The neural cell adhesion molecule (N-CAM) is a group of cell surface glycoproteins involved in direct cell--cell adhesion. N-CAM expression in normal and neoplastic tissues was examined with specific antibodies and oligonucleotide probes by immunohistochemistry and in situ hybridization. Most neuroendocrine cells and tumors with secretory granules expressed N-CAM protein and mRNA. Parathyroid adenomas (4) were somewhat unusual, because N-CAM mRNA, but not protein, was detected in some of these… CONTINUE READING
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