Expression of netrin-1 and its receptors DCC and neogenin in rat brain after ischemia.

@article{Tsuchiya2007ExpressionON,
  title={Expression of netrin-1 and its receptors DCC and neogenin in rat brain after ischemia.},
  author={Atsushi Tsuchiya and Takeshi Hayashi and Kentaro Deguchi and Yoshihide Sehara and Toru Yamashita and Hanzhe Zhang and Violeta Lukic and Makiko Nagai and Tatsushi Kamiya and Koji Abe},
  journal={Brain research},
  year={2007},
  volume={1159},
  pages={1-7}
}
It is very important to investigate the mechanism of axonal growth in the ischemic brain in order to consider a novel mean of therapy for stroke. Netrins are chemotropic factors for axon with chemoattractant or chemorepellant guidance activities, and deleted in colorectal cancer (DCC) and neogenin are receptors for netrins. In this study, we examined expressions of netrin-1, DCC, and neogenin in the brain after 90 min of transient middle cerebral artery occlusion (tMCAO). Netrin-1 was expressed… CONTINUE READING

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