Expression of neonatal Fc receptor in the eye.


PURPOSE The neonatal Fc receptor (FcRn) plays a critical role in the homeostasis and degradation of immunoglobulin G (IgG). It mediates the transport of IgG across epithelial cell barriers and recycles IgG in endothelial cells back into the bloodstream. These functions critically depend on the binding of FcRn to the Fc domain of IgG. The half-life and… (More)
DOI: 10.1167/iovs.13-12574


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@article{Powner2014ExpressionON, title={Expression of neonatal Fc receptor in the eye.}, author={Michael B. Powner and Jenny A.G. McKenzie and Gregory J. Christianson and Derry Charles Roopenian and Marcus Fruttiger}, journal={Investigative ophthalmology & visual science}, year={2014}, volume={55 3}, pages={1607-15} }