Expression of myosin heavy chain isoforms in skeletal muscle of patients with peripheral arterial occlusive disease.

Abstract

PURPOSE Peripheral arterial occlusive diseases (PAODs) not only compromise blood flow but lead to a series of subsequent metabolic and structural changes in the relevant muscles. Changes in myofibrillar proteins (eg, of myosin heavy chain [MHC] isoforms), one of the determinants of muscle structure as well as of muscular function, have not been reported in… (More)

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