Expression of myosin heavy chain isoforms in skeletal muscle of patients with peripheral arterial occlusive disease.


PURPOSE Peripheral arterial occlusive diseases (PAODs) not only compromise blood flow but lead to a series of subsequent metabolic and structural changes in the relevant muscles. Changes in myofibrillar proteins (eg, of myosin heavy chain [MHC] isoforms), one of the determinants of muscle structure as well as of muscular function, have not been reported in… (More)


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