Expression of multiple gamma-glutamyltransferase genes in man.

  title={Expression of multiple gamma-glutamyltransferase genes in man.},
  author={C{\'e}line Courtay and Nora Heisterkamp and G{\'e}rard Siest and John Groffen},
  journal={The Biochemical journal},
  volume={297 ( Pt 3)},
In clinical and pharmacological laboratories, the assay for gamma-glutamyltransferase (GGT) activity is an important diagnostic test, but one with high biological variability. Although the human genome contains multiple GGT genomic sequences, the diagnostic tests generally assume that only a single GGT gene is active. In the current study, segments encompassing parts of seven different potential human GGT genes have been molecularly cloned. Based on sequence determination of exons within these… CONTINUE READING