Expression of multidrug resistance 1 and multidrug resistance-related protein 1 in C57BL/6 mice treated with benzene.

@article{Huang2013ExpressionOM,
  title={Expression of multidrug resistance 1 and multidrug resistance-related protein 1 in C57BL/6 mice treated with benzene.},
  author={J S Huang and M-D Zhao and J-M Shi and J Zhang and B. Li and Wei Fan and Y Zhou},
  journal={Genetics and molecular research : GMR},
  year={2013},
  volume={12 4},
  pages={5842-50}
}
ATP-binding cassette super family (ABC) proteins are considered key to oncology and pharmacology studies. We examined the effect of benzene on ABC pump protein levels in C57BL/6 mouse bone marrow mononuclear cells. After a 2-week gavage (200 mg/kg, 5 days per week), the number of peripheral leukocytes, lymphocytes and basophils dropped significantly; there… CONTINUE READING