Expression of mucosal chemokines TECK/CCL25 and MEC/CCL28 during fetal development of the ovine mucosal immune system.

@article{Meurens2007ExpressionOM,
  title={Expression of mucosal chemokines TECK/CCL25 and MEC/CCL28 during fetal development of the ovine mucosal immune system.},
  author={François Meurens and Julia Whale and Robert Brownlie and Tova Dybvig and David R. Thompson and Volker Gerdts},
  journal={Immunology},
  year={2007},
  volume={120 4},
  pages={544-55}
}
CCL25/TECK and CCL28/MEC are CC chemokines primarily expressed in thymic dendritic cells and mucosal epithelial cells. The cognate receptors of CCL25 and CCL28, CCR9 and CCR10, respectively, are mainly expressed on T and B lymphocytes. In human, mouse and pig, CCL25 and CCL28 play a key role in the segregation and the compartmentalization of the mucosal immune system through recruitment of immune cells to specific locations. However, little is known about their role in the ontogeny of the… CONTINUE READING
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