Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.

@article{Rock2005ExpressionOM,
  title={Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.},
  author={Rebecca E Rock and Sabrina Schrauth and Manfred Gessler},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2005},
  volume={234 3},
  pages={747-55}
}
The dachsous (ds), fat (ft), and four-jointed (fj) genes have been identified in Drosophila as part of a signaling pathway that regulates planar cell polarity (PCP). A homologous PCP signaling pathway has also been identified in vertebrates, but nothing is known thus far about the conservation of Ds/Ft/Fj signaling. Here we analyzed and compared for the first time the expression patterns of all ds, ft and fj homologs in the mouse. During embryogenesis, expression analysis was performed by RNA… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 38 extracted citations

Regulation of leg size and shape: involvement of the Dachsous-fat signaling pathway.

Developmental dynamics : an official publication of the American Association of Anatomists • 2011
View 4 Excerpts
Highly Influenced

The expression of Fat-1 cadherin during chick limb development.

The International journal of developmental biology • 2007
View 4 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…