Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat

@article{Kim1995ExpressionOM,
  title={Expression of monocyte chemoattractant protein-1 and macrophage inflammatory protein-1 after focal cerebral ischemia in the rat},
  author={Jong S. Kim and Subhash C. Gautam and Michael Chopp and Cecylia Zaloga and Michael L. Jones and Peter A. Ward and Kenneth M. A. Welch},
  journal={Journal of Neuroimmunology},
  year={1995},
  volume={56},
  pages={127-134}
}
Overexpression of Monocyte Chemoattractant Protein 1 in the Brain Exacerbates Ischemic Brain Injury and is Associated with Recruitment of Inflammatory Cells
  • Yong Chen, J. Hallenbeck, S. Vogel
  • Biology, Medicine
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
  • 2003
TLDR
Brain infarction volumes after ischemia were significantly larger in MBP-JE mice than in wild-type controls and were accompanied by increased local transmigration and perivascular accumulation of macrophages and neutrophils, indicating that MCP-1 can contribute to inflammatory injury in stroke.
Hypoxic-Ischemic Injury Induces Monocyte Chemoattractant Protein-1 Expression in Neonatal Rat Brain
TLDR
The results suggest that in the developing brain, MCP-1 could represent a functionally important molecular signal for the microglial response to hypoxic-ischemic injury.
Chemokine and Inflammatory Cell Response to Hypoxia-Ischemia in Immature Rats
TLDR
The expression of mRNA for α- and β-chemokines preceded the appearance of immune cells suggesting that these molecules may have a role in the inflammatory response to insults in the immature central nervous system.
Differential production of MCP‐1 and cytokine‐induced neutrophil chemoattractant in the ischemic brain after transient focal ischemia in rats
TLDR
It is suggested that MCP‐1 in cerebral ischemia actually plays a significant role in the migration of macrophages into the lesion and that the differential temporal production of these chemokines contributes to the regulation of infiltrated leukocyte subtypes.
MIP-1alpha and MCP-1 Induce Migration of Human Umbilical Cord Blood Cells in Models of Stroke.
TLDR
MCP-1 and MIP-1alpha expression were significantly increased in the ischemic hemisphere of brain, and significantly promoted HUCB cell migration compared to the contralateral side, suggesting that the increased chemokines in theIschemic area can bind cell surface receptors on H UCB, and induce cell infiltration of systemically delivered HUCBs cells into the CNS in vivo.
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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TLDR
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