Expression of monocyte chemoattractant protein 1 mRNA in human idiopathic pulmonary fibrosis.

@article{Antoniades1992ExpressionOM,
  title={Expression of monocyte chemoattractant protein 1 mRNA in human idiopathic pulmonary fibrosis.},
  author={Harry N. Antoniades and J Neville-Golden and T Galanopoulos and Richard L Kradin and Anthony J Valente and Dana T Graves},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1992},
  volume={89 12},
  pages={
          5371-5
        }
}
Macrophages are thought to play an important role in the pathologic changes associated with idiopathic pulmonary fibrosis (IPF). The mechanisms for increased monocyte/macrophage recruitment in IPF are unknown. Monocyte chemoattractant protein 1 (MCP-1) is the predominant monocyte chemoattractant secreted by a variety of different cell types in culture. We examined the expression of MCP-1 mRNA and its protein product in vivo in IPF and non-IPF lung specimens by in situ hybridization and… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 95 CITATIONS, ESTIMATED 59% COVERAGE

Latent infection by γherpesvirus stimulates profibrotic mediator release from multiple cell types.

  • American journal of physiology. Lung cellular and molecular physiology
  • 2011
VIEW 16 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis.

  • American journal of respiratory and critical care medicine
  • 2009
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

1993
2018

CITATION STATISTICS

  • 6 Highly Influenced Citations