Expression of monocarboxylate transporter (MCT) 1 and MCT4 in overloaded mice plantaris muscle

@article{Kitaoka2011ExpressionOM,
  title={Expression of monocarboxylate transporter (MCT) 1 and MCT4 in overloaded mice plantaris muscle},
  author={Yu Kitaoka and Masanao Machida and Tohru Takemasa and Hideo Hatta},
  journal={The Journal of Physiological Sciences},
  year={2011},
  volume={61},
  pages={467-472}
}
A number of studies have shown that changes in muscle contractile activity regulate the expression of monocarboxylate transporters (MCTs) in the skeletal muscle. The aim of this study was to investigate the effect of functional overload on MCT1 and MCT4 protein expression. Plantaris muscles were functionally overloaded for 15 days by ablation of the synergistic muscles. MCT1 and MCT4 mRNA abundance increased by 160–161% (p < 0.01) and 265–325% (p < 0.05), respectively, after 1–3 days of… CONTINUE READING
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