Expression of microsomal prostaglandin E2 synthase-1 and its role in human hepatocellular carcinoma.


Microsomal prostaglandin E2 synthase-1 (mPGES1), an inducible enzyme similar to cyclooxygenase-2, functions downstream of cyclooxygenase-2 in the synthesis of prostaglandin E2. It contributes to carcinogenesis in a variety of tumors. Here, mPGES1 expression was assessed using immunohistochemistry of tissue microarrays containing a total of 100… (More)
DOI: 10.1016/j.humpath.2013.04.007


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