Expression of microRNAs of C19MC in Different Histological Types of Testicular Germ Cell Tumour.

@article{Flor2016ExpressionOM,
  title={Expression of microRNAs of C19MC in Different Histological Types of Testicular Germ Cell Tumour.},
  author={Inga Flor and Meike Spiekermann and Thomas Loening and Klaus-Peter Dieckmann and Gazanfer Belge and Joern Bullerdiek},
  journal={Cancer genomics & proteomics},
  year={2016},
  volume={13 4},
  pages={
          281-9
        }
}
BACKGROUND Testicular germ cell tumours (TGCTs) are the most common tumours in men aged from 20 to 40 years, with a steadily increasing incidence. This study aimed to characterize the expression of the miRNA cluster C19MC in TGCT and to evaluate the suitability of a C19MC miRNA as a serum biomarker. MATERIALS AND METHODS By quantitative reverse transcription PCR, we measured the expression of miR-517a-3p, miR-519a-3p, and miR-519c 3p in tissue samples of 25 TGCTs and the level of miR-517a-3p… CONTINUE READING
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