Expression of metastasis-related genes in human epithelial ovarian tumors.

  title={Expression of metastasis-related genes in human epithelial ovarian tumors.},
  author={Carlos A Herrera and Lei Xu and Corazon D. Bucana and El Vio G Silva and Kenneth R. Hess and David M. Gershenson and Isaiah Josh Fidler},
  journal={International journal of oncology},
  volume={20 1},
We examined the expression level of several genes that regulate distinct steps of metastasis in 55 formalin-fixed, paraffin-embedded, archival specimens of primary human ovarian carcinoma from patients undergoing curative surgery. The expression of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF), basic fibroblast growth factor (bFGF), E-cadherin, type IV collagenase, matrix metalloproteinase (MMP-2 and MMP-9), and interleukin 8 (IL-8) was examined by a colorimetric in… CONTINUE READING


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