Expression of metalloproteinases MMP-2 and MMP-9 in antrochoanal polyps.

  title={Expression of metalloproteinases MMP-2 and MMP-9 in antrochoanal polyps.},
  author={Ozg{\"u}l Topal and Selim Sermed Erbek and Halil Kiyici and Ozcan Cakmak},
  journal={American journal of rhinology},
  volume={22 4},
BACKGROUND Matrix metalloproteinase (MMP) 2 and MMP-9 are known to cleave specifically type 4 collagen, which is a major structural component of basement membrane. This is an early step of inflammation. Because of this property they have been studied in chronic sinonasal disorders. The aim of this study was to determine the MMP-2 and MMP-9 expressions in an antrochoanal polyp (ACP). METHODS We examined tissue samples from 10 ACPs, 10 diffuse nasal polyps, and 10 control nasal mucosa (CM) by… CONTINUE READING

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