Expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) on prostate cancer cell lines.

@article{Nagakawa2000ExpressionOM,
  title={Expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) on prostate cancer cell lines.},
  author={O. Nagakawa and K. Murakami and T. Yamaura and Y. Fujiuchi and J. Murata and H. Fuse and I. Saiki},
  journal={Cancer letters},
  year={2000},
  volume={155 2},
  pages={
          173-9
        }
}
Membrane-type metalloproteinase-1 (MT1-MMP) is a transmembrane metalloproteinase, which activates proMMP-2 and expressed on the cell surface in many invasive cancer cells. We investigated the expression of MT1-MMP in prostate cancer cell lines. MT1-MMP protein and mRNA were expressed in PC-3, DU-145 and TSU-pr1 cells (androgen-independent prostate cancer cell lines), but in LNCaP cells (androgen-dependent prostate cancer cell line). MT1-MMP protein was negative and mRNA was low to detect by RT… Expand
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