Expression of megakaryocytic and erythroid properties in human leukemic cells.

@article{Tani1996ExpressionOM,
  title={Expression of megakaryocytic and erythroid properties in human leukemic cells.},
  author={Takashi Tani and Jari Yl{\"a}nne and Ismo Virtanen},
  journal={Experimental hematology},
  year={1996},
  volume={24 2},
  pages={158-68}
}
Previous studies have suggested that megakaryocytes and erythrocytes may share a common precursor cell. However, studies on the commitment to erythroid and megakaryocytic lineages have been hampered by the lack of suitable human leukemic cell lines having this kind of bipotential differentiation capability. We investigated the coexpression of megakaryocytic and erythroid markers in human leukemic cell lines as well as the capability of these cells to further differentiate upon exposure to… CONTINUE READING

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