Expression of matrix metalloproteinases in the subretinal fluid correlates with the extent of rhegmatogenous retinal detachment

@article{Symeonidis2006ExpressionOM,
  title={Expression of matrix metalloproteinases in the subretinal fluid correlates with the extent of rhegmatogenous retinal detachment},
  author={Chrysanthos Symeonidis and Eudoxia Diza and Eleni D Papakonstantinou and Efimia Souliou and George Karakiulakis and Stavros Dimitrakos},
  journal={Graefe's Archive for Clinical and Experimental Ophthalmology},
  year={2006},
  volume={245},
  pages={560-568}
}
We investigated the activity of matrix metalloproteinase (MMP)−2 and −9 and the protein levels of MMP−1, −3, −8 and the tissue inhibitor of MMPs (TIMP)−1 in the subretinal fluid (SRF) of patients with rhegmatogenous retinal detachment (RRD) and establishment of potential correlations with clinical parameters. Thirty-seven SRF from RRD patients and nine vitreous samples from the human eye of organ donors (controls) were collected and assayed for MMP−1,−3,−8 and TIMP−1 levels using ELISA and for… CONTINUE READING