Expression of matrix metalloproteinases in ovarian endometriomas: immunohistochemical study and enzyme immunoassay.

@article{Mizumoto2002ExpressionOM,
  title={Expression of matrix metalloproteinases in ovarian endometriomas: immunohistochemical study and enzyme immunoassay.},
  author={Hisanobu Mizumoto and Tsuyoshi Saito and Koji Ashihara and Makoto Nishimura and Masaki Takehara and Ryouichi Tanaka and Eiki Ito and Ryuichi Kudo},
  journal={Life sciences},
  year={2002},
  volume={71 3},
  pages={259-73}
}
Like carcinoma, endometriosis has the unique characteristics, of invasion and metastasis, though pathologically, it is a benign tumor. However, the mechanism of destruction of the surrounding tissue in endometriosis is still unclear. In this study, the expression and localization of matrix metalloproteinases (MMP)-1, -2, -3, -7, -9 and tissue inhibitors of metalloproteinases-1 (TIMP-1) were evaluated by immunohistochemistry for 20 cases and the amounts of MMP-1, TIMP-1 and MMP-1/TIMP-1 complex… CONTINUE READING
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