Expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinase 1 and 2 in inflammation-induced corneal neovascularization.

@article{Ma2001ExpressionOM,
  title={Expression of matrix metalloproteinases 2 and 9 and tissue inhibitors of metalloproteinase 1 and 2 in inflammation-induced corneal neovascularization.},
  author={Dzwokai Ma and Jennifer K Chen and Won Seog Kim and Yunfeng Hao and Henry Cheng-ju Wu and Ray Jui-fang Tsai and D. S. Hwang and Fen Zhang},
  journal={Ophthalmic research},
  year={2001},
  volume={33 6},
  pages={353-62}
}
PURPOSE Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase (TIMPs) have been linked to the angiogenic process in general. In order to understand the potential roles of MMP-2, MMP-9 and TIMPs in the corneal neovascularization process, we examined the expression and activities of MMP-2, MMP-9 and TIMPs during the course of cauterization-induced corneal neovascularization in a rat model. METHODS Neovascularization of rat corneas was induced by silver nitrate… CONTINUE READING

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