Expression of matrix metalloproteinase-9 in high-grade salivary gland carcinomas is associated with their metastatic potential.

@article{Vicente2008ExpressionOM,
  title={Expression of matrix metalloproteinase-9 in high-grade salivary gland carcinomas is associated with their metastatic potential.},
  author={Juan C de Vicente and Paloma Lequerica-Fern{\'a}ndez and Juan Sebasti{\'a}n L{\'o}pez-Arranz and I Esteban and Manuel Florentino Fresno and Aurora Astudillo},
  journal={The Laryngoscope},
  year={2008},
  volume={118 2},
  pages={247-51}
}
OBJECTIVE The aim of this study was to investigate the role of matrix metalloproteinase (MMP)-9 protein in high-grade malignant tumors of salivary gland origin as well as its utility as a prognostic marker. METHODS Four micrometer sections from 27 malignant salivary neoplasms were immunostained using a specific antibody against MMP-9. The staining results (proportion of the stained tumor cells and intensity of tumor stainings) were correlated with the clinical data and with patient outcomes… CONTINUE READING

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