Expression of matrix metalloproteinase-9 and -12 in porcine lung infections.

  title={Expression of matrix metalloproteinase-9 and -12 in porcine lung infections.},
  author={Camilla Sichlau Bruun and P{\'a}ll Sk{\'u}li Leifsson and Louise Kruse Johansen and Henrik Elvang Jensen and Jens J\orgen Nielsen and Merete Fredholm},
  journal={Journal of comparative pathology},
  volume={146 2-3},
Matrix metalloproteinases (MMPs) play a variety of roles during organogenesis, in the immune response and during acute and chronic diseases as well as in tissue remodelling. During the last decade, the pig has become used increasingly as a model for human diseases; however, studies on the expression of porcine MMPs are limited. In the present study species-specific antibodies were produced to investigate the expression of MMP-9 and MMP-12 immunohistochemically in lungs from pigs infected with… CONTINUE READING