Expression of matrix metalloproteinase-3 in stage I and II squamous cell carcinoma of the oral cavity.

@article{Kusukawa1995ExpressionOM,
  title={Expression of matrix metalloproteinase-3 in stage I and II squamous cell carcinoma of the oral cavity.},
  author={Jingo Kusukawa and Yasuyuki Sasaguri and Minoru Morimatsu and Tadamitsu Kameyama},
  journal={Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons},
  year={1995},
  volume={53 5},
  pages={
          530-4
        }
}
PURPOSE The object of this study was to evaluate the significance of matrix metalloproteinase-3 (MMP-3) in tumor invasion and metastasis of early squamous cell carcinoma (SCC) of the oral cavity. MATERIALS AND METHODS Surgical specimens from 65 patients with stage I and II SCC of the oral cavity were the subjects of this study. Tissue specimens were fixed in formalin and embedded in paraffin, and the sections were stained with monospecific antibodies against human MMP-3 by the avidin-biotin… CONTINUE READING

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